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Cancer pain can be managed with medication, relaxation techniques, and other procedures. Medication Acetaminophen: An over-the-counter pain reliever for mild pain Nonsteroidal anti-inflammatory drugs (NSAIDs): Such as ibuprofen (Advil) or naproxen (Aleve) for mild pain Opioids: Such as morphine (Kadian, Ms Contin) or oxycodone (Oxycontin, Roxicodone) for moderate to severe pain Other prescription drugs: Such as antidepressants, antiseizure drugs, muscle relaxants, or steroids Relaxation techniques massage, tai chi, yoga, hypnotherapy, meditation, acupuncture, relaxation exercises, and music-based interventions. Other procedures Nerve block A numbing medicine is injected around or into a nerve to stop pain signals from being sent to the brain Intrathecal pump A small, round device that holds pain medicine and is surgically placed under the skin at the side of the abdomen Physical therapy Personalized exercise and treatment programs to help increase physical activity Pain assessment The first step in pain management is to talk with your cancer care team about any pain you may be having.